Brown roast in skillet on all sides; remove to roasting pan, reserving pan drippings. Add water, Heinz 57 sauce, soy sauce, salt and pepper to reserved pan drippings; mix well. Pour over roast. Roast at 375° for 1 hour. Baste with pan drippings. Reduce oven temperature to 300°. Roast for 1 hour longer, basting occasionally with pan drippings.