Shake flour in the oven bag; place in an ungreased 13x9x2-inch baking pan. Combine the Worcestershire sauce, garlic salt, onion salt, pepper and liquid smoke; rub over both sides of brisket. Place in the oven bag. Close with tie and refrigerate for 8 hours or overnight, turning occasionally. Combine ketchup, brown sugar, lemon juice, mustard and hot pepper sauce; spread over brisket. Close oven bag with nylon tie; cut 6 - 1/2-inch slits in top of bag. Return to pan. Bake at 325° for 3-4 hours or until beef is tender.